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Caspase-2
英文名：Rabbit Monoclonal IgG
Cas号：
Cas号：
检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113400-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | CASP-2, ICH-1 protease, NEDD2 protein, Neural precurs o r cell expressed developmentally down-regulated protein 2, NEDD-2 |
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| 产品参数 | 【产品介绍】Caspase-2 (Nedd2/ICH-1) is part of a family
of aspartate-specific cysteine proteases that participate in programmed cell death, o r apoptosis. Caspase-2 is localized to the nucleus, a n d has been shown to play roles in both positive a n d negative regulation of apoptosis (1). Upon apoptotic stimulation, pro-caspase-9 is cleaved in a series of steps to produce an 18-kDa large subunit a n d a 12-kDa small fragment (2). Caspase-2 can be a nuclear initiat o r caspase, as it has been shown to precede the processing a n d activation of caspase-8, -9, a n d -3 (3). Caspase-2 might also act as an effect o r caspase; in apoptotic pathways resulting from UV-induced DNA damage, processing of caspase-2 occurs downstream of caspase-9 a n d caspase-3 activation (4). WB: 1:500 IP: 1:20 A. Western blot analysis on Jurkat cell lysate using anti-Caspase-2 RabMAb (catalog #1552-1), dilution 1:500. |
| 性状 | 【反应特异性】Human
【克隆 ID】Y154 【用途】WB , IP 【抗原分子量】48/18 kDa |
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