Integrin beta-1/CD29

英文名:ITGB1
Cas号:
检测信息查询
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别 名 Fibronectin recept o r subunit beta, Integrin VLA-4 subunit beta, CD29 antigen
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】Integrin beta-1 (ITGB1, CD29, VLA-beta) is
the beta subunit found in the integrin families, f o r
ming a heterodimer integrin recept o r through
non-covalent bonding with various integrin alpha
subunits. Integrin heterodimer containing Integrin
beta-1 binds to various cell surface a n d
extracellular proteins (CD49a-f, CD51) to mediate cell
to cell a n d cell to matrix adhesion (1). Integrin
beta-1 plays a critical role in the cell adhesion
a n d recognition in embryogenesis, hemostasis,
immune response, tissue repair, metastatic diffusion of
tum o r cells a n d development (2, 3, 4).

Recommended Applications
WB, IHC, FC
Applications and Recommended Dilution Factors
WB: 1:500
IHC: 1:100 - 250
FC: 1:10 - 100
Species Reactivity *
Human
*Cross reactivity determined by western blot only.

Products Data

A. Western blot analysis on (A) U937 and (B) HeLa
cell lysates using anti-Integrin beta-1 Rabbit
Monoclonal (cat. # 2288-1), at dilution 1:500.

C. Immunohistochemical analysis of paraffin-embedded
human hepatocellular carcinoma using anti-CD29 RabMAb
(cat# 2288-1).

B. Immunohistochemical analysis of paraffin-embedded
human brain (endothelial cells) using anti-Integrin beta
1 RabMAb.

Specificity
A synthetic peptide corresponding to the residues in
human Integrin beta-1 (CD29) was used as immunogen.
性状 【产品类型】Rabbit Monoclonal IgG
【反应特异性】Human
【克隆 ID】EPR1040Y
【用途】WB , IHC , FC
【产品性状】
【阳性对照】
【产品浓度】
【细胞定位】
【抗原分子量】140 - 150 kDa
贮存 Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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